Article
Noninvasive, in vivo approaches to evaluating behavior and exercise physiology in mouse models of mitochondrial disease.
Methods (San Diego, Calif.) - 1 Apr 2002
Graham Brett H, David Sweatt J, Craigen William J
Abstract excerpt
Mitochondrial diseases are a clinically heterogeneous group of disorders related to dysfunction of various components of oxidative metabolism. Common manifestations of these diseases include encephalopathy, skeletal myopathy, and cardiomyopathy, but essentially any tissue can be affected. To understand better the pathogenesis of mitochondrial disease and to potentially evaluate novel therapies, several mouse...
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