Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Graded Maximal Exercise Testing to Assess Mouse Cardio-Metabolic Phenotypes.

PloS one - 1 Jan 2016

Petrosino Jennifer M, Heiss Valerie J, Maurya Santosh K, Kalyanasundaram Anuradha, Periasamy Muthu, LaFountain Richard A, Wilson Jacob M, Simonetti Orlando P, Ziouzenkova Ouliana

Abstract excerpt

Functional assessments of cardiovascular fitness (CVF) are needed to establish animal models of dysfunction, test the effects of novel therapeutics, and establish the cardio-metabolic phenotype of mice. In humans, the graded maximal exercise test (GXT) is a standardized diagnostic for assessing CVF and mortality risk. These tests, which consist of concurrent staged increases in running speed and inclination,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exercise Test

Share to Mice, Inbred C57BL

Share to Myocardium

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26859763
DOI: 10.1371/journal.pone.0148010
PMCID: PMC4747552

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Graded Maximal Exercise Testing to Assess Mouse Cardio-Metabolic Phenotypes.PMID 26859763Read ↗

Inter- and intrastrain variation in mouse critical running speedSemantic proximity Read ↗

Exercise assessment of transgenic models of human cardiovascular diseaseSemantic proximity Read ↗

A treadmill exercise regimen for identifying cardiovascular phenotypes in transgenic mice.Semantic proximity Read ↗

Novel quantitative phenotypes of exercise training in mouse models.Semantic proximity Read ↗

Sexually dimorphic skeletal muscle and cardiac dysfunction in a mouse model of limb girdle muscular dystrophy 2i.Semantic proximity Read ↗

Drosophila Endurance Training and Assessment of Its Effects on Systemic AdaptationsSemantic proximity Read ↗

Noninvasive, in vivo approaches to evaluating behavior and exercise physiology in mouse models of mitochondrial disease.Semantic proximity Read ↗

Quantitative trait loci associated with maximal exercise endurance in mice.Semantic proximity Read ↗

Exercise Capacity and Response to Training Quantitative Trait Loci in a NZW X 129S1 Intercross and Combined Cross Analysis of Inbred Mouse Strains.Semantic proximity Read ↗

Selective breeding for high voluntary exercise in mice increases maximal (V̇O2,max) but not basal metabolic rate.Semantic proximity Read ↗

Derivation of ultrasound and electrocardiogram cardiac reference ranges for Mus musculus using the collaborative cross and identification of new cardiac models.Semantic proximity Read ↗

Identification of exercise capacity QTL using association mapping in inbred mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.