Article
Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.
Circulation - 28 Nov 2017
Gibb Andrew A, Epstein Paul N, Uchida Shizuka, Zheng Yuting, McNally Lindsey A, Obal Detlef, Katragadda Kartik, Trainor Patrick, Conklin Daniel J, Brittian Kenneth R, Tseng Michael T, Wang Jianxun, Jones Steven P, Bhatnagar Aruni, Hill Bradford G
Abstract excerpt
BACKGROUND: Exercise promotes metabolic remodeling in the heart, which is associated with physiological cardiac growth; however, it is not known whether or how physical activity-induced changes in cardiac metabolism cause myocardial remodeling. In this study, we tested whether exercise-mediated changes in cardiomyocyte glucose metabolism are important for physiological cardiac growth. METHODS: We used...
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