Article
Role of the Bordetella pertussis minor fimbrial subunit, FimD, in colonization of the mouse respiratory tract.
Infection and immunity - 1 Oct 1997
Geuijen C A, Willems R J, Bongaerts M, Top J, Gielen H, Mooi F R
Abstract excerpt
Bordetella pertussis fimbriae are composed of a major subunit, Fim2 or Fim3, and the minor subunit FimD. Using immunoelectron microscopy, we provide evidence that FimD is located at the fimbrial tip. The role of FimD in colonization of the mouse respiratory tract was studied by using two fimbrial...
Topics
- Adhesins, Bacterial
- Animals
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Bordetella pertussis
- Disease Models, Animal
- Fimbriae Proteins
- Fimbriae, Bacterial
- Hemagglutinins
- Lung
- Mice
- Mice, Inbred BALB C
- Mutation
- Nasopharynx
- Protein Binding
- Trachea
- Virulence Factors, Bordetella