Article
Construction of an MR/P fimbrial mutant of Proteus mirabilis: role in virulence in a mouse model of ascending urinary tract infection.
Infection and immunity - 1 Aug 1994
Bahrani F K, Massad G, Lockatell C V, Johnson D E, Russell R G, Warren J W, Mobley H L
Abstract excerpt
Proteus mirabilis, a cause of acute pyelonephritis, produces at least four types of fimbriae, including MR/P (mannose-resistant/Proteus-like) fimbriae. To investigate the contribution of MR/P fimbriae to colonization of the urinary tract, we constructed an MR/P fimbrial mutant by allelic exchange...
Topics
- Animals
- Bacterial Proteins
- Female
- Fimbriae, Bacterial
- Genetic Complementation Test
- Kidney
- Mice
- Mutation
- Proteus Infections
- Proteus mirabilis
- Pyelonephritis
- Urinary Tract Infections