Article
Construction and analysis of Bordetella pertussis mutants defective in the production of fimbriae.
Microbial pathogenesis - 1 Feb 1992
Mooi F R, Jansen W H, Brunings H, Gielen H, van der Heide H G, Walvoort H C, Guinee P A
Abstract excerpt
Although the role of fimbriae in bacterial disease has been well established, little is known about the function of Bordetella pertussis fimbriae. To study this function, well-defined fimbrial mutants were constructed. B. pertussis harbours three fimbrial genes, fim2, fim3 and fimX, and strains w...
Topics
- Animals
- Blotting, Southern
- Bordetella pertussis
- Cloning, Molecular
- Fimbriae, Bacterial
- Male
- Mice
- Mice, Inbred BALB C
- Mutation
- Restriction Mapping
- Whooping Cough