Article
Bordetella pertussis fimbriae bind to human monocytes via the minor fimbrial subunit FimD.
The Journal of infectious diseases - 1 Apr 1995
Hazenbos W L, Geuijen C A, van den Berg B M, Mooi F R, van Furth R
Abstract excerpt
Nonopsonized Bordetella pertussis can bind to and become ingested by human monocytes. Previous studies demonstrated that mutant B. pertussis strains that lack fimbriae express a reduced adherence to monocytes. The present study was undertaken to investigate the involvement of the minor fimbrial subunit FimD in the adherence of B. pertussis to human monocytes using purified fimbriae, FimD, and strains with...
Topics
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Bordetella pertussis
- Carrier Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- Flow Cytometry
- Genes, Bacterial
- Humans
- Lymphocytes