Article
Contribution of the major and minor subunits to fimbria-mediated adherence of Haemophilus influenzae to human epithelial cells and erythrocytes.
Infection and immunity - 1 Dec 1995
van Ham S M, van Alphen L, Mooi F R, van Putten J P
Abstract excerpt
Fimbriae are colonization factors of the human pathogen Haemophilus influenzae in that they mediate bacterial adherence to human eukaryotic cells. The contribution of the major (HifA) and putative minor (HifD and HifE) subunits of H. influenzae fimbriae to fimbria-specific adherence was studied by using mutants that were inactivated in distinct fimbrial genes. Both the major and minor subunits were required for...
Topics
- Adult
- Bacterial Adhesion
- Bacterial Proteins
- Epithelium
- Erythrocytes
- Fimbriae Proteins
- Fimbriae, Bacterial
- Haemophilus influenzae
- Humans
- Multigene Family
- Mutation