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Article

Mutations of mitochondrial DNA - cause or consequence of the ageing process?

Zeitschrift fur Gerontologie und Geriatrie - 1 Oct 2007

Meissner C

Abstract excerpt

Ageing is a stochastic process which leads to a gradual decline in cellular, tissue and even organ function, especially in energy dependent postmitotic tissues like skeletal muscle, brain and heart. The mitochondrial theory of ageing is based on the assumption that reactive oxygen species (ROS) and free radicals generated in the immediate vicinity of the electron transport chain during the lifespan of an organism...

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PMID: 17943235
DOI: 10.1007/s00391-007-0481-z

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POLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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