Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid-Dependent Transcriptional Repression of the Osteocalcin Gene by Competitive Binding at the TATA Box

1 Aug 1997

Abstract excerpt

The human osteocalcin gene is transcriptionally repressed by glucocorticoids. A specific binding element for the glucocorticoid receptor (GR) overlapping the TATA box of the human osteocalcin promoter has previously been identified. In the present study, the function of this element has been further characterized by competitive gel mobility-shift assay and transfection experiments. The GR and TATA-binding protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Estrogen and related hormone effects
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9303434
DOI: 10.1089/dna.1997.16.919

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid-Dependent Transcriptional Repression of the Osteocalcin Gene by Competitive Binding at the TATA BoxPMID 9303434Read ↗

The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation.Semantic proximity Read ↗

Competition between glucocorticoid receptor and NFκB for control of the human FasL promoterSemantic proximity Read ↗

The structural basis of direct glucocorticoid-mediated transrepression.Semantic proximity Read ↗

Heterodimerization between the glucocorticoid receptor and the unrelated DNA-binding protein, Xenopus glucocorticoid receptor accessory factor.Semantic proximity Read ↗

The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction.Semantic proximity Read ↗

Synthetic Glucocorticoids That Dissociate Transactivation and AP-1 Transrepression Exhibit Antiinflammatory Activity<i>in Vivo</i>Semantic proximity Read ↗

Allosteric Effects of Dexamethasone and RU486 on Glucocorticoid Receptor-DNA InteractionsSemantic proximity Read ↗

Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells.Semantic proximity Read ↗

Transcription of the human thyrotropin-releasing hormone receptor gene-analysis of basal promoter elements and glucocorticoid response elements.Semantic proximity Read ↗

Glucocorticoid Repression of AP-1 Is Not Mediated by Competition for Nuclear CoactivatorsSemantic proximity Read ↗

Protein-protein interactions facilitate DNA binding by the glucocorticoid receptor DNA-binding domain.Semantic proximity Read ↗

Interaction of C/EBPα and the glucocorticoid receptor in vivo and in nontransformed human cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.