Article
Protein-protein interactions facilitate DNA binding by the glucocorticoid receptor DNA-binding domain.
The Journal of biological chemistry - 15 Aug 1990
Dahlman-Wright K, Siltala-Roos H, Carlstedt-Duke J, Gustafsson J A
Abstract excerpt
We have studied the interaction of the DNA-binding domain of the glucocorticoid receptor with a glucocorticoid response element from the tyrosine aminotransferase gene. This response element consists of two binding sites (half-sites) for the glucocorticoid receptor DNA-binding domain. The sequences of these two half-sites are not identical, and we have previously shown that binding occurs preferentially to one of...
Topics
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- Escherichia coli
- Genes
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Protein Binding