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Article

Early genetic and functional events in the pathogenesis of oral cancer.

Radiation oncology investigations - 1 Jan 1997

Prime S S, Eveson J W, Guest P G, Parkinson E K, Paterson I C

Abstract excerpt

Oral squamous cell carcinoma (SCC) is a major world health problem, but the changes leading to the development of malignancy remain essentially unknown. Early changes are thought to include the loss of tumour suppressor genes on chromosomes 3p, 9p, and 17p. Although what genes are involved on chromosome 3 remains speculative, p16 (9p21) and p53 (17p13) are inactivated in a high proportion of oral dysplastic...

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Source

Identifiers

PMID: 9303062
DOI: 10.1002/(sici)1520-6823(1997)5:3<93::aid-roi1>3.0.co;2-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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