Article
Squamous carcinoma of the head and neck: molecular mechanisms and potential biomarkers.
The Australian and New Zealand journal of surgery - 1 Aug 2000
Rose B R, Thompson C H, Tattersall M H, O'Brien C J, Cossart Y E
Abstract excerpt
Squamous cell carcinoma (SCC) of the head and neck remains a major health problem worldwide. Recent advances in cell biology suggest that cancer results from the accumulation of specific genetic mutations, many of which have now been identified. These mutations can cause the activation of genes that promote cellular proliferation or inhibit cell death (oncogenes), or they may inactivate genes that inhibit...
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