Article
Oral cancer in the molecular age.
Journal of the California Dental Association - 1 Aug 2001
Regezi J A, Jordan R C
Abstract excerpt
Oral cancer represents an accumulation of defects in the genes that encode key proteins associated with growth and development. Dysregulation of these proteins is central to malignant conversion. This appears to involve three major changes in cell function: 1. altered cell growth, death and longevity; 2. unencumbered cell movement; and 3. development of a new blood supply (angiogenesis). Specific genes, such as...
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