Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentiation of CD4(high)CD8(low) coreceptor-skewed thymocytes into mature CD8 single-positive cells independent of MHC class I recognition.

European journal of immunology - 1 Aug 1997

Barthlott T, Kohler H, Pircher H, Eichmann K

Abstract excerpt

Thymocytes with a CD4(hi)CD8(lo) coreceptor-skewed (CRS) phenotype have been shown to contain precursors for CD8 single-positive (SP) thymocytes, in addition to precursors for CD4 SP cells. The selection mechanisms that stimulate CD4(hi)CD8(lo) cells to revert to the CD8 lineage are not known. Mice transgenic (tg) for the major histocompatibility complex (MHC) class I-restricted P14 T cell receptor (TCR), on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Lymphocyte Activation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mice, Inbred C57BL

Share to Mice, Transgenic

Share to Phenotype

Share to Pregnancy

Source

Identifiers

PMID: 9295041
DOI: 10.1002/eji.1830270829

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentiation of CD4(high)CD8(low) coreceptor-skewed thymocytes into mature CD8 single-positive cells independent of MHC class I recognition.PMID 9295041Read ↗

The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes.Semantic proximity Read ↗

CD8αα intraepithelial lymphocytes arise from two main thymic precursors.Semantic proximity Read ↗

Thymocyte Selection Regulates the Homeostasis of IL-7–Expressing Thymic Cortical Epithelial Cells In VivoSemantic proximity Read ↗

The late stage of T cell development within mouse thymus.Semantic proximity Read ↗

Identification of pre- and postselection TCRalphabeta+ intraepithelial lymphocyte precursors in the thymus.Semantic proximity Read ↗

Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.Semantic proximity Read ↗

Maturation and emigration of single-positive thymocytes.Semantic proximity Read ↗

Identification and characterization of pro-T lymphocytes and lineage-uncommitted lymphocyte precursors from mice with three novel surface markers.Semantic proximity Read ↗

T cell development: new approaches.Semantic proximity Read ↗

Recent thymic emigrants are distinct from most medullary thymocytes.Semantic proximity Read ↗

Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymusSemantic proximity Read ↗

Human postnatal thymocytes generate phenotypically immature CD3dim, CD5dim, CD1abright progeny in organ culture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.