Article
Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.
PloS one - 1 Jan 2013
Dong Jie, Chen Yu, Xu Xi, Jin Rong, Teng Fei, Yan Fan, Tang Hui, Li Pingping, Sun Xiuyuan, Li Yan, Wu Hounan, Zhang Yu, Ge Qing
Abstract excerpt
After a tightly regulated developmental program in the thymus, "mature" single positive (SP) thymocytes leave the thymus and enter the periphery. These newly arrived recent thymic emigrants (RTEs) are phenotypically and functionally immature, and will complete a dynamic maturation in the peripheral lymphoid organs before being licensed to be resident naïve T cells. To study the early events occurring in the RTE...
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