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Article

Cytotoxic T cell reactivity and HLA-B35 binding of the variant Plasmodium falciparum circumsporozoite protein CD8+ CTL epitope in naturally exposed Kenyan adults.

European journal of immunology - 1 Aug 1997

Udhayakumar V, Ongecha J M, Shi Y P, Aidoo M, Orago A S, Oloo A J, Hawley W A, Nahlen B L, Hoffman S L, Weiss W R, Lal A A

Abstract excerpt

In this study, we have investigated the extent of natural polymorphism in the CD8+ cytotoxic T lymphocyte (CTL) determinant (amino acids 368-390) of circumsporozoite (CS) protein of Plasmodium falciparum field isolates from a holoendemic region of Kenya, and determined how this variation affects the CTL reactivities in clinically immune adults and binding specificities to human histocompatibility leukocyte...

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Identifiers

PMID: 9295031
DOI: 10.1002/eji.1830270819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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