Article
In silico study to predict promiscuous T cell and B cell-epitopes derived from the vaccine candidate antigens of Plasmodium vivax binding to MHC class-II alleles.
Journal of vector borne diseases - 1 Jan 2000
Khan Nazam, Bin-Mwena Mona N, Alruways Mashael W, Allehyani Noor Motair M, Alanzi Maryam Owaid, Shahzad, Khan Amir, Sehgal Rakesh, Tripathi P K, Farooq Umar
Abstract excerpt
Malaria is one of the major causes of health and disability globally, even after tremendous efforts to eradicate it. Till date no highly effective vaccine is available for its control. The primary reason for the low efficacy of vaccines is extensive polymorphism in potential vaccine candidate antigen genes and HLA polymorphisms in the human population. This problem can be resolved by developing a vaccine using...
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