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Article

c-Fos is an intracellular regulator of cocaine-induced long-term changes.

Annals of the New York Academy of Sciences - 1 Oct 2008

Xu Ming

Abstract excerpt

Development of drug addiction is accompanied by the induction of long-lasting neurobiological changes. Dopamine D1 receptors are involved in mediating cocaine-induced neuroadaptation, yet the underlying intracellular mechanisms remain less clear. Using a genetically modified mouse in which Fos is primarily mutated in D1 receptor-bearing neurons in the brain, we examined a potential role of the immediate early...

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Identifiers

PMID: 18991842
DOI: 10.1196/annals.1432.049
PMCID: PMC2596070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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