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Article

Perinatal lethality in H19 enhancers-Igf2 transgenic mice.

Molecular reproduction and development - 1 Oct 1997

Wise T L, Pravatcheva D D

Abstract excerpt

The insulin-like growth factor II (IGFII) is a mitogen for a number of cell types in vitro and is required for normal embryonic growth. It has been hypothesized that overexpression of IGF2 is responsible for the increased growth and tumor predisposition in patients with Beckwith-Wiedemann syndrome. Association of increased levels of IGFII with increased growth is also incorporated in a current model for the...

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Identifiers

PMID: 9291469
DOI: 10.1002/(SICI)1098-2795(199710)48:2<194::AID-MRD7>3.0.CO;2-N

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Perinatal lethality in H19 enhancers-Igf2 transgenic mice.PMID 9291469Read ↗

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Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA.Semantic proximity Read ↗

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