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Article

Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer.

International journal of cancer - 22 Aug 1997

Erber R, Klein W, Andl T, Enders C, Born A I, Conradt C, Bartek J, Bosch F X

Abstract excerpt

p21(CIP1/WAF1) is an inhibitor of cyclin-dependent kinases and, in normal tissues including squamous epithelia, has been associated with cell-cycle exit and differentiation. As shown in this pilot study, however, the majority of head-and-neck squamous-cell carcinomas (HNSCC) display aberrant p21(CIP1/WAF1) expression: of 42 tumors analyzed by immunohistochemical staining, 28 (67%) over-expressed the...

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PMID: 9291426
DOI: 10.1002/(sici)1097-0215(19970822)74:4<383::aid-ijc4>3.0.co;2-r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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