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Article

Evidence for a deficiency of interferon response in mononuclear cells from hepatitis C viremic patients.

Journal of hepatology - 1 Aug 1997

Podevin P, Guechot J, Serfaty L, Monrand-Joubert L, Veyrunes C, Bonnefis M T, Poupon R

Abstract excerpt

BACKGROUND/AIMS: The pathophysiology of chronic hepatitis C and the mechanisms of resistance to interferon alpha are poorly understood. The aim of this work was to assess the influence of HCV infection and the viral genotype on lymphocyte production of 2',5' oligo-adenylate synthetase activity and monocyte production of TNF alpha and IL1 beta. METHODS: Mononuclear cells from 50 consecutive patients were studied...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9288599
DOI: 10.1016/s0168-8278(97)80170-5

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for a deficiency of interferon response in mononuclear cells from hepatitis C viremic patients.PMID 9288599Read ↗

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Clinical relevance of the 2'-5'-oligoadenylate synthetase/RNase L system for treatment response in chronic hepatitis C.Semantic proximity Read ↗

Inflammation and repair in viral hepatitis C.Semantic proximity Read ↗

Activation of Type I and Type III Interferons in Chronic Hepatitis C.Semantic proximity Read ↗

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