Article
Activation of Type I and Type III Interferons in Chronic Hepatitis C.
Journal of innate immunity - 1 Jan 2015
Mihm Sabine
Abstract excerpt
Infection with hepatitis C virus (HCV) results in chronic and progressive liver disease. Persistency rates add up to 85%. Despite recognition of the virus by the human host in peripheral blood and in the liver, immune response appears to be ineffective in clearing infection. The ability to spontaneously eradicate the virus as well as the outcome of infection upon therapy with human recombinant interferon-α...
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