Article
Inflammation and repair in viral hepatitis C.
Digestive diseases and sciences - 1 Jun 2008
Neuman Manuela G, Sha Kevin, Esguerra Rustan, Zakhari Sam, Winkler Robert E, Hilzenrat Nir, Wyse Jonathan, Cooper Curtis L, Seth Devanshi, Gorrell Mark D, Haber Paul S, McCaughan Geoffrey W, Leo Maria A, Lieber Charles S, Voiculescu Mihai, Buzatu Eugenia, Ionescu Camelia, Dudas Jozsef, Saile Bernhard, Ramadori Giuliano
Abstract excerpt
Hepatitis C viral infection (HCV) results in liver damage leading to inflammation and fibrosis of the liver and increasing rates of hepatic decompensation and hepatocellular carcinoma (HCC). However, the host's immune response and viral determinants of liver disease progression are poorly understood. This review will address the determinants of liver injury in chronic HCV infection and the risk factors leading to...
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