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Article

Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema.

Lancet (London, England) - 30 Aug 1997

Smith C A, Harrison D J

Abstract excerpt

BACKGROUND: The first-pass metabolism of foreign compounds in the lung is an important protective mechanism against oxidative stress. We investigated whether polymorphisms in the gene for microsomal epoxide hydrolase (mEPHX), an enzyme involved in this protective process, had any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease (COPD) and emphysema. METHODS: We...

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Identifiers

PMID: 9288046
DOI: 10.1016/S0140-6736(96)08061-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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