Article
Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses.
Respirology (Carlton, Vic.) - 1 Nov 2008
Hu Guoping, Shi Zhe, Hu Jinxing, Zou Guoming, Peng Gongyong, Ran Pixin
Abstract excerpt
BACKGROUND AND OBJECTIVE: COPD is a complex polygenic disease in which gene-environment interactions are very important. The gene encoding microsomal epoxide hydrolase (EPHX1) is one of several candidate loci for COPD pathogenesis and is highly polymorphic. Based chi on the polymorphisms of EPHX1 gene (tyrosine/histidine 113, histidine/arginine 139), the population can be classified into four groups of putative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
