Article
Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1.
Thorax - 1 Feb 2000
Yim J J, Park G Y, Lee C T, Kim Y W, Han S K, Shim Y S, Yoo C G
Abstract excerpt
BACKGROUND: Although smoking is the major causal factor in the development of chronic obstructive pulmonary disease (COPD), only 10-20% of chronic heavy cigarette smokers develop symptomatic COPD which suggests the presence of genetic susceptibility. This genetic susceptibility to COPD might depend on variations in enzyme activities that detoxify cigarette smoke products such as microsomal epoxide hydrolase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.