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Article

Microsomal epoxide hydrolase gene polymorphisms and susceptibility to chronic obstructive pulmonary disease in the Tunisian population.

Genetic testing and molecular biomarkers - 1 Dec 2010

Lakhdar Ramzi, Denden Sabri, Knani Jalel, Leban Nadia, Daimi Houria, Hassine Mohsen, Lefranc Gérard, Chibani Jemni Ben, Khelil Amel Haj

Abstract excerpt

It is well known that cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). However, only 10%-20% of chronic heavy cigarette smokers develop symptomatic disease, which suggests the presence of genetic susceptibility. Microsomal epoxide hydrolase (EPHX1) is an enzyme involved in the protective mechanism against oxidative stress. It has been reported that gene polymorphisms of...

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Identifiers

PMID: 20932192
DOI: 10.1089/gtmb.2009.0168

Genes

EPHX1

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