Human colorectal cancer: high frequency of deletions at chromosome 1p35.

Article

Human colorectal cancer: high frequency of deletions at chromosome 1p35.

Cancer research - 15 Nov 1990

Leister I, Weith A, Brüderlein S, Cziepluch C, Kangwanpong D, Schlag P, Schwab M

Abstract excerpt

Cytogenetic analyses of human colon cancer cells have revealed a high frequency of chromosome 1p deletions among other chromosomal abnormalities. In order to find out whether these chromosomal alterations are manifestations of loss of genetic material, we surveyed DNA of 62 primary tumors, 7 meta...

Topics

Alleles
Carcinoma
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 1
Colorectal Neoplasms
DNA Probes
Heterozygote
Humans
Polymorphism, Restriction Fragment Length

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