Article
The effects of human macrophage inflammatory protein-1 alpha and its genetically modified variant, BB10010, on phagocyte function.
Cytokines, cellular & molecular therapy - 1 Mar 1997
Williams S L, Addison I E, Mollapour E, Czaplewski L G, Linch D C, Roberts P J
Abstract excerpt
BB-10010 is a genetically modified form of human macrophage inflammatory protein-1 alpha (MIP-1 alpha) with a single amino acid substitution of Asp26 by alanine, which inhibits aggregation of the native molecule. BB-10010 has stem cell protective properties, and has entered clinical trials for th...
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