Article
Reprogramming of a subpopulation of human blood neutrophils by prolonged exposure to cytokines.
Laboratory investigation; a journal of technical methods and pathology - 1 Oct 2009
Chakravarti Arpita, Rusu Daniel, Flamand Nicolas, Borgeat Pierre, Poubelle Patrice E
Abstract excerpt
Essential cells of innate immunity, neutrophils are often considered to be a homogenous population of terminally differentiated cells. During inflammation, neutrophils are extravasated cells exposed to local factors that prolong their survival and activate their production of mediators implicated in disease progression. In this study, a phenotypically distinct subset of human neutrophils that appear after...
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