Article
Multiple Phenotypic Changes Define Neutrophil Priming.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Miralda Irina, Uriarte Silvia M, McLeish Kenneth R
Abstract excerpt
Exposure to pro-inflammatory cytokines, chemokines, mitochondrial contents, and bacterial and viral products induces neutrophils to transition from a basal state into a primed one, which is currently defined as an enhanced response to activating stimuli. Although, typically associated with enhanced generation of reactive oxygen species (ROS) by the NADPH oxidase, primed neutrophils show enhanced responsiveness of...
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