Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LacZ and Interleukin-3 Expression <i>In Vivo</i> after Retroviral Transduction of Marrow-Derived Human Osteogenic Mesenchymal Progenitors

10 Aug 1997

Abstract excerpt

Human marrow-derived mesenchymal progenitor cells (hMPCs), which have the capacity for osteogenic and marrow stromal differentiation, were transduced with the myeloproliferative sarcoma virus (MPSV)-based retrovirus, vM5LacZ, that contains the LacZ and neo genes. Stable transduction and gene expression occurred in 18% of cells. After culture expansion and selection in G418, approximately 70% of neor hMPCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9287142
DOI: 10.1089/hum.1997.8.12-1417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LacZ and Interleukin-3 Expression <i>In Vivo</i> after Retroviral Transduction of Marrow-Derived Human Osteogenic Mesenchymal ProgenitorsPMID 9287142Read ↗

Human Mesenchymal Stem Cells Maintain Transgene Expression during Expansion and DifferentiationSemantic proximity Read ↗

Efficient Lentiviral Transduction and Improved Engraftment of Human Bone Marrow Mesenchymal CellsSemantic proximity Read ↗

Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imagingSemantic proximity Read ↗

Fates and osteogenic differentiation potential of human mesenchymal stem cells in immunocompromised mice.Semantic proximity Read ↗

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivoSemantic proximity Read ↗

<i>In Vivo</i> Evaluation of Gene Therapy Vectors in <i>Ex Vivo</i> -Derived Marrow Stromal Cells for Bone Regeneration in a Rat Critical-Size Calvarial Defect ModelSemantic proximity Read ↗

Establishing an immortalized human osteoprecursor cell line: OPC1.Semantic proximity Read ↗

Generation of Directly Converted Human Osteoblasts That Are Free of Exogenous Gene and Xenogenic Protein.Semantic proximity Read ↗

Developmental-like bone regeneration by human embryonic stem cell-derived mesenchymal cells.Semantic proximity Read ↗

In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals.Semantic proximity Read ↗

Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapySemantic proximity Read ↗

Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.