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Human Mesenchymal Stem Cells Maintain Transgene Expression during Expansion and Differentiation

1 Jun 2001

Abstract excerpt

Human adult bone marrow contains both hematopoietic stem cells that generate cells of all hematopoietic lineages and human mesenchymal stem cells (hMSCs), which support hematopoiesis and contribute to the regeneration of multiple connective tissues. The goal of the current study was to demonstrate that transduced hMSCs maintain transgene expression after stem cell differentiation in vitro and in vivo. We have...

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PMID: 11407899
DOI: 10.1006/mthe.2001.0327

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