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<i>In Vivo</i> Evaluation of Gene Therapy Vectors in <i>Ex Vivo</i> -Derived Marrow Stromal Cells for Bone Regeneration in a Rat Critical-Size Calvarial Defect Model

10 Dec 2003

Abstract excerpt

Cells genetically modified to produce osteoinductive factors have potential for use in enhancing bone regeneration for reconstructive applications. Genetic modification of cells can be accomplished by a variety of gene therapy vectors. In this study we evaluated the ex vivo genetic modification of rat marrow stromal cells (MSCs) by adenoviral, retroviral, and cationic lipid vectors containing the gene for human...

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PMID: 14670121
DOI: 10.1089/104303403322611719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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