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Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging

31 Dec 2008

Abstract excerpt

Mesenchymal stem cells (MSCs) can differentiate into osteogenic, adipogenic, chondrogenic, myocardial, or neural lineages when exposed to specific stimuli, making them attractive for tissue repair and regeneration. We have used reporter gene-based imaging technology to track MSC transplantation or implantation in vivo. However, the effects of lentiviral transduction with the fluc-mrfp-ttk triple-fusion vector on...

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PMID: 19116247
DOI: 10.1152/physiolgenomics.00300.2007

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