Article
Three determinants in ezrin are responsible for cell extension activity.
Molecular biology of the cell - 1 Aug 1997
Martin M, Roy C, Montcourrier P, Sahuquet A, Mangeat P
Abstract excerpt
The ERM proteins--ezrin, radixin, and moesin--are key players in membrane-cytoskeleton interactions. In insect cells infected with recombinant baculoviruses, amino acids 1-115 of ezrin were shown to inhibit an actin- and tubulin-dependent cell-extension activity located in ezrin C-terminal domain (ezrin310-586), whereas full-length ezrin1-586 did not induce any morphological change. To refine the mapping of...
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