Article
Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy.
Journal of molecular biology - 27 Jul 2001
Ishikawa H, Tamura A, Matsui T, Sasaki H, Hakoshima T, Tsukita S, Tsukita S
Abstract excerpt
The function of ERM (ezrin/radixin/moesin) proteins as general cross-linkers between actin filaments and plasma membranes is regulated downstream of Rho, through the transition between active and inactive forms. To directly examine the conformational change between the active and inactive forms of ERM proteins, we applied low-angle rotary-shadowing electron microscopy to the radixin molecules, wild-type,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.