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Article

Activated protein C resistance phenotype in patients with antiphospholipid antibodies.

The Journal of laboratory and clinical medicine - 1 Aug 1997

Aznar J, Villa P, España F, Estellés A, Grancha S, Falcó C

Abstract excerpt

The effect of antiphospholipid antibodies (aPL) on the action of activated protein C (APC) was examined in 32 patients: 19 with lupus anticoagulant (LA), 6 with anticardiolipin antibodies (aCL), and 7 with LA and aCL. Eighteen patients had a ratio of activated partial thromboplastin time (APTT) with APC to APTT without APC (APTT ratio) <2.06 (cut-off level) and no factor V Leiden mutation; these patients showed...

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Source

Identifiers

PMID: 9280148
DOI: 10.1016/s0022-2143(97)90097-4

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Activated protein C resistance phenotype in patients with antiphospholipid antibodies.PMID 9280148Read ↗

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[Analysis of phenotype resistance to activated protein C (APC resistance)].Semantic proximity Read ↗

Inherited resistance to activated protein C, a major cause of venous thrombosis, is due to a mutation in the factor V gene.Semantic proximity Read ↗

Activated protein C resistance in patients with peripheral vascular disease.Semantic proximity Read ↗

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Use of modified functional assays for activated protein C resistance in patients with basally prolonged aPTT.Semantic proximity Read ↗

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