Article
Activated-protein-C resistance in cancer patients.
Haemostasis - 1 Jan 2000
Green D, Maliekel K, Sushko E, Akhtar R, Soff G A
Abstract excerpt
BACKGROUND: Resistance to activated protein C (aPC) is usually linked to factor V Leiden, but may occur in other disorders associated with hypercoagulability. In this study, we investigated the frequency of resistance to aPC in patients with advanced cancer and examined the relationship of aPC resistance to other markers of coagulation activation. METHODS: Patients (n = 39) had established diagnosis of advanced...
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