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Article

Models for pairing of IS10 encoded antisense RNAs in vivo.

Journal of theoretical biology - 21 Jun 1997

Jain C

Abstract excerpt

Antisense regulation of IS10 transposase synthesis is mediated by a small RNA molecule, RNA-OUT which is complementary to the 5' region of the IS10 transposase mRNA, RNA-IN. Pairing between the two species in vivo prevents initiation of RNA-IN translation by steric occlusion of the ribosome binding site. The goal of this work is to develop a mathematical basis for antisense repression in vivo. Thus, by modeling...

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Source

Identifiers

PMID: 9278719
DOI: 10.1006/jtbi.1996.0371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 8 closest

Models for pairing of IS10 encoded antisense RNAs in vivo.PMID 9278719Read ↗

IS10 antisense control in vivo is affected by mutations throughout the region of complementarity between the interacting RNAs.Semantic proximity Read ↗

The IS10 antisense RNA blocks ribosome binding at the transposase translation initiation site.Semantic proximity Read ↗

Control of translation by mRNA secondary structure: the importance of the kinetics of structure formation.Semantic proximity Read ↗

Antisense RNAs in bacteria and their genetic elements.Semantic proximity Read ↗

Decay of the IS10 antisense RNA by 3' exoribonucleases: evidence that RNase II stabilizes RNA-OUT against PNPase attack.Semantic proximity Read ↗

Preferential cis action of IS10 transposase depends upon its mode of synthesis.Semantic proximity Read ↗

Using in-cell SHAPE-Seq and simulations to probe structure-function design principles of RNA transcriptional regulators.Semantic proximity Read ↗

RNA biochemistry. Determination of in vivo target search kinetics of regulatory noncoding RNA.Semantic proximity Read ↗

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