Article
A simple method to reveal possible ras mutations in DNA of urinary sediment cells.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 1997
Cristaudo A, Vivaldi A, Guglielmi G, Sensales G, Ottenga F
Abstract excerpt
Occupational and environmental exposure to carcinogens is reported to be responsible for 25% of all bladder tumors. Among many genetic alterations found in tumor bladder cells, chromosome aberrations and mutations of some oncogenes, such as ras genes, are common. Studies conducted to determine the rate and type of ras mutations involved reported rather contrasting results. Researchers agree that among the three...
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