Article
Expression of HLA class I molecules assembled with structural variants of human beta2-microglobulin.
Immunogenetics - 1 Jan 1997
Trymbulak W P, Zeff R A
Abstract excerpt
Mouse and human beta2-microglobulin (beta2m), which differ by 30% in their primary sequence, give rise to disparate levels of HLA class I heavy chain expression in transfectants of the beta2m-null FO-1 human melanoma cell line, i.e., mouse beta2m directs expression of HLA class I heavy chains that is only approximately 20%-30% of that observed for heavy chains assembled with human beta2m. In this report we...
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