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Article

Mutants of human beta2-microglobulin map an immunodominant epitope within the three-stranded beta-pleated sheet.

Transplantation - 27 Aug 1997

Trymbulak W P, Zeff R A

Abstract excerpt

Genetically engineered structural variants of human beta2-microglobulin (beta2m) were produced by sequence exchange with mouse beta2m for the purpose of examining species-specific antigenic determinant expression. For aggregate mapping, mouse and human beta2m, which differ by 30% in their primary sequence of 99 amino acids, were prepared as chimeric (human X mouse) molecules and expressed in the FO-1 beta2m-null...

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Identifiers

PMID: 9293879
DOI: 10.1097/00007890-199708270-00016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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