Article
Altered pulmonary response to hyperoxia in Clara cell secretory protein deficient mice.
American journal of respiratory cell and molecular biology - 1 Aug 1997
Johnston C J, Mango G W, Finkelstein J N, Stripp B R
Abstract excerpt
Clara cell secretory protein (CCSP) is an abundant component of the extracellular lining fluid of airways. Even though the in vivo function of CCSP is unknown, in vitro studies support a potential role of CCSP in the control of inflammatory responses. CCSP-deficient mice (CCSP -/-) were generated to investigate the in vivo function of this protein (13). In this study, we used hyperoxia exposure as a model to...
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