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Article

Genetic variation in the tumor necrosis factor alpha gene and the outcome of multiple sclerosis.

Neurology - 1 Aug 1997

Weinshenker B G, Wingerchuk D M, Liu Q, Bissonet A S, Schaid D J, Sommer S S

Abstract excerpt

The objective of this study was to determine whether sequence variation in the tumor necrosis factor alpha (TNF alpha) gene is associated with MS course and severity in Olmsted County, MN. The severity and temporal course of MS are heterogeneous. Genetic factors may play a role in determining the course of MS. TNF alpha expression is temporally associated with exacerbations of MS and is increased in individuals...

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PMID: 9270565
DOI: 10.1212/wnl.49.2.378

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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