Article
Fast 5-hour determination of angiotensin-converting enzyme genotypes from blood by SDS-PAGE using PhastSystem.
Clinica chimica acta; international journal of clinical chemistry - 8 Aug 1997
Huang X H, Koivula T, Ilveskoski E, Karhunen P J, Rantalaiho V, Wirta O, Pasternack A, Lehtimäki T
Abstract excerpt
Polymorphism in the angiotensin-converting enzyme (ACE) gene has been shown to correlate with circulating ACE concentrations in plasma, and also to be an independent risk factor in the development of many cardiovascular diseases. However, methods available today for ACE genotyping are still laborious and time-consuming. Here we report a sensitive, simple and non-isotopic procedure with commercially available gels...
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