Rapid methods for population-scale analysis for gene polymorphisms: the ACE gene as an example.

doi:10.1136/hrt.73.4.368

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Article

Rapid methods for population-scale analysis for gene polymorphisms: the ACE gene as an example.

British heart journal - 1 Apr 1995

O'Dell S D, Humphries S E, Day I N

Abstract excerpt

OBJECTIVE: To obtain rapid, high throughput genotyping of the angiotensin converting enzyme (ACE) gene intron 16 insertion/deletion polymorphism. METHODS: DNA was obtained from whole blood samples by a simple liquid phase methanol extraction procedure. The ACE gene was amplified by the polymerase...

Topics

Alleles
Cardiovascular Diseases
Electrophoresis, Polyacrylamide Gel
Genotype
Humans
Introns
Mass Screening
Peptidyl-Dipeptidase A
Polymerase Chain Reaction
Polymorphism, Genetic

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