Article
Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors.
Journal of neuro-oncology - 1 Sept 2000
Schiebe M, Ohneseit P, Hoffmann W, Meyermann R, Rodemann H P, Bamberg M
Abstract excerpt
Malignant gliomas are the most frequent primary brain tumors. Recent studies defined several genetic markers, which might characterize molecular-biological subsets of glioblastomas with probably prognostic implications. To elucidate the involvement of murine-double-minute (mdm)2 gene amplificatio...
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