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Article

Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism.

Annals of internal medicine - 20 Apr 1999

Rodeghiero F, Tosetto A

Abstract excerpt

BACKGROUND: Resistance to activated protein C due to the factor V R506Q (Leiden) mutation is the most common clotting abnormality in patients with venous thromboembolism. OBJECTIVE: To evaluate the risk for venous thromboembolism associated with the factor V Leiden mutation or with resistance to...

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Source

Identifiers

PMID: 10215560
DOI: 10.7326/0003-4819-130-8-199904200-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10215560-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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